r4 - 17 Jul 2007 - 02:47:10 - LorenEveyYou are here: TWiki >  Archive Web > AtlasDemos > UrinarySystem4 > ProximalConvolutedTubuleL4

Proximal Convoluted Tubule (PCT)

The filtrate formed in Bowman's space flows towards the urinary pole to enter the proximal tubule. The proximal tubule consists of an initial convoluted portion (the proximal convoluted tubule) and a distal straight portion (the pars recta). In cross section, the tubular epithelial cells are simple cuboidal cells, with a prominent brush border (microvilli) and basal striations (elongated mitochondria) (R-P, Figs. 20.10, 20.14, 20.15 & Pl. 72). The PCTs often have star-shaped lumens, which are generally larger in diameter than the distal tubules (see below). Cells of the PCT are generally more eosinophilic than cells of other tubules in the kidney, and stain particularly well with PAS (B-66, PAS [10x, 20x, 40x]; B-67, H&E [10x, 20x, 40x-labeled]; B-68, PAS [10x, 20x, 40x-labeled]; B-71, H&E [10x, 20x, 40x-labeled]). Try to identify PCTs. Also, examine regions near glomeruli in order to identify urinary poles in longitudinal section that are continuous with a PCT.

Proximal Convoluted Tubule Identifications

b66_renal_cortex_10x_pas.jpg b66_renal_cortex_20x_pas.jpg b66_renal_cortex_40x_pas.jpg b67_renal_cortex_10x.jpg
B66, PCT, 10x (PAS) . B66, PCT, 20x (PAS) . B66, PCT, 40x (PAS) . B67, PCT, 10x (H&E) .
b67_renal_cortex_20x.jpg b67_renal_cortex_40x_labeled.jpg b68_proximal_convoluted_tubule_kidney_10x_pas.jpg b68_proximal_convoluted_tubule_kidney_20x_pas.jpg
B67, PCT, 20x (H&E) . B67, PCT, 40x Labeled (H&E) . B68, PCT, 10x (PAS) . B68, PCT, 20x (PAS) .
b68_proximal_convoluted_tubule_kidney_40x_pas_labeled.jpg b71_renal_tubules_10x_he.jpg b71_renal_tubules_20x_he.jpg b71_renal_tubules_40x_he_labeled.jpg
B68, PCT, 40x Labeled (PAS) . B71, PCT, 10x (H&E) . B71, PCT, 20x (H&E) . B71, PCT, 40x Labeled (H&E) .


Rowup Structure Abbreviation Optimal Stain Representative Section Note
1 Proximal Convoluted Tubule PC   B68, PCT, 40x Labeled (PAS)  
2 Distal Convoluted Tubule DC   B68, PCT, 40x Labeled (PAS)  
3 Brush Border BB   B68, PCT, 40x Labeled (PAS)  
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-- AshleyLPistorio - 23 May 2007

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