r10 - 17 Jul 2007 - 03:11:30 - LorenEveyYou are here: TWiki >  Archive Web > AtlasDemos > LayoutThree > RenalCorpuscleL3

Renal Corpuscle

Study a section of the kidney, referring to R-P, Figs. 20.1, 20.3, 20.6 & Pl. 70. In the cortex, locate a renal (Malpighian) corpuscle (slide B-67, H&E [2.5x-labeled, 10x, 20x, 40x]; B-68, PAS [2.5x, 10x, 20x, 40x-labeled]; B-69, PAS [2.5x, 10x, 20x, 40x]; B-70, carmine [2.5x-labeled, 10x, 20x, 40x-labeled]; B-71, H&E [2.5x, 10x, 20x, 40x]).

A renal corpuscle is the invaginated blind end of a renal tubule called Bowman's capsule. The capsule is composed of a simple squamous epithelium referred to as the parietal layer. Internally (the visceral layer) is a capillary tuft, the glomerulus, and specialized cells (refer to R-P, Fig. 20.7 & Pls. 71 & 72) that are intimately associated with the capillary tuft. These cells are the podocytes. In H&E stained sections the podocytes are difficult to see but have pale cytoplasm, and lightly stained, slightly larger, oval nuclei. The podocytes extend finger-like processes (pedicels) that wrap around the capillaries. Between the pedicels are basal lamina-covered slits that act as a filter, allowing fluid from the blood to enter the corpuscle. In the electron microscope, podocytes are seen to consist of a central cell body and numerous foot processes applied to the basal lamina of the capillary. Note the pores between the foot processes and fenestrations in the capillary wall (R-P, Figs. 20.8 & 20.11). The other major cell type within the corpuscle is the mesangial cell. These cells are difficult to distinguish from endothelial cells. Between the visceral and parietal layers of Bowman's capsule is Bowman's space, which fills up with the filtrate.

The corpuscle is a polarized structure with a vascular pole and a urinary pole (RP, Fig. 20.7). At the vascular pole, the vessel bringing blood to the glomerulus is called the afferent arteriole, and the vessel taking blood away is called the efferent arteriole. These vessels anchor the glomerulus to the wall of Bowman's capsule.


b67_renal_corpuscle_2x_he_labeled.jpg b67_renal_corpuscle_10x_he.jpg b67_renal_corpuscle_20x_he.jpg b67_renal_corpuscle_40x_he.jpg
B67, Renal Corpuscle, 2.5x Labeled (H&E) . B67, Renal Corpuscle, 10x (H&E) . B67, Renal Corpuscle, 20x (H&E) . B67, Renal Corpuscle, 40x (H&E) .
b68_renal_corpuscle_2x_pas.jpg b68_renal_corpuscle_10x_pas.jpg b68_renal_corpuscle_20x_pas.jpg b68_renal_corpuscle_40x_pas_labeled.jpg
B68, Renal Corpuscle, 2.5x (PAS) . B68, Renal Corpuscle, 10x (PAS) . B68, Renal Corpuscle, 20x (PAS) . B68, Renal Corpuscle, 40x Labeled (PAS) .
b69_renal_corpuscle_2x_pas.jpg b69_renal_corpuscle_10x_pas.jpg b69_renal_corpuscle_20x_pas.jpg b69_renal_corpuscle_40x_pas.jpg
B69, Renal Corpuscle, 2.5x (PAS) . B69, Renal Corpuscle, 10x (PAS) . B69, Renal Corpuscle, 20x (PAS) . B69, Renal Corpuscle, 40x (PAS) .
b70_renal_corpuscle_2x_carmine.jpg b70_renal_corpuscle_10x_carmine.jpg b70_renal_corpuscle_20x_carmine.jpg b70_renal_corpuscle_40x_carmine_labeled.jpg
B70, Renal Corpuscle, 2.5x (Carmine) . B70, Renal Corpuscle, 10x (Carmine) . B70, Renal Corpuscle, 20x (Carmine) . B70, Renal Corpuscle, 40x Labeled (Carmine) .
b71_renal_corpuscle_2x_he.jpg b71_renal_corpuscle_10x_he.jpg b71_renal_corpuscle_20x_he.jpg b71_renal_corpuscle_40x_he.jpg
B71, Renal Corpuscle, 2.5x (H&E) . B71, Renal Corpuscle, 10x (H&E) . B71, Renal Corpuscle, 20x (H&E) . B71, Renal Corpuscle, 40x (H&E) .

TheKidneyL3

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Comments

 
  • In the end, I would make the kidney introduction the parent of this topic. This would make the navigation bar more useful. Then, I think we should discuss passing on the manual TOC. There is merit to the "back to parent" link because you do not have to go to the top of the page to use the navigation bar. In this particular case, however, it seems to me that the parent is the kidney introduction and not layer three. -- LorenEvey - 22 May 2007
  • I was considering that option (in All Urinary System Slides)... but also thinking it will be a good way to also have a "review" of slides in one show. The labels I am using are from Comments, and I have a lot of options here so that as you go through the slide show you can see which chapter it's in (as above, they are all called "...Renal Corpuscle...". I did this generically so I don't have to create new Galleries and I can just link several topics to one in the review section.
  • So, would you rather there be two sections in the main chapter page- 1. All Urinary System Slides (separate thumbs for each subchapter), and 2. A Review of the Urinary System (all thumbs in one Gallery)? I can easily only have one thumb on the front page and when you click it, you start the slide show (at least, I think I can do that-- by limiting the number of thumbs displayed I believe I do not limit the actual gallery of enlarged images). -- AshleyLPistorio - 22 May 2007
  • Regarding the "up" navigation link. Can there be multiple galleries on a page? If so, you could use subheadings to define gallery groupings and improve upon the " All Urinary System Slides" solution in Layout2. There could be 6 galleries named for chapter/subheading on one page. The TOC would allow quick access to each gallery. -- LorenEvey - 22 May 2007
  • This is a test of the thumbnail links - B71, Renal Corpuscle, 40x (H&E). It works. Thus far, I am liking layout_3 moreso than layout_2. -- LorenEvey - 22 May 2007
  • In the case of the labeled images it appears that the label key is non-vector. There might be a way to use a form or template so that you can use screen fonts for the key. This should improve readability. -- LorenEvey - 21 May 2007
  • Well, this should give us something to think about. It looks like this plugin might make better use of screen space when viewing the image. I don't suppose you can right justify the image and place additional explanatory text to the left? Or, otherwise word wrap? Please take the practice examination at the VotePlugin Sandbox. I can only vote once. I want to see what happens with two votes. -- LorenEvey - 21 May 2007
  • This adds some interesting options-- including a "slide show review" when you click on the thumbs. Two birds, one stone. It is much bulkier than the other Thumbs plugin but it addresses one of the questions of thumb titles without having to hover.
Comments, questions, breadsticks? -- AshleyLPistorio - 21 May 2007 Begin Topic

-- AshleyLPistorio - 21 May 2007

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Archive.RenalCorpuscleL3 moved from Main.RenalCorpuscleL3 on 17 Jul 2007 - 07:06 by LorenEvey - put it back
 
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