The straight portion of the proximal tubule (pars recta) enters a medullary ray and
descends toward the medulla. Both parts of the proximal tubule are lined by cuboidal
epithelial cells. The next tubular segment that the filtrate passes through is the thin tubule
or thin loop of Henle which is mainly located in the medulla. Here the diameter of the
tubule narrows markedly and the epithelium becomes simple squamous (see R-P, Fig.
20.17 & Pl. 73 or R-K-P, Fig. 19.17 & Pl. 73). The thin segment descends toward the
apex of the pyramid. Before reaching the apex of the pyramid, however, it makes a
hairpin turn and returns toward the cortex. Don’t confuse the thin segments of the
tubules with the capillaries they associate with. Tubular epithelial cells are somewhat
thicker, tubular diameter is somewhat greater, and the tubules do not contain RBCs. The
next tubular segment is the distal thick tubule. The distal thick segment ascends through
the medullary ray as the straight ascending segment. The straight ascending segment
exits the medullary ray and returns to its corpuscle of origin.
Try to identify each of these tubules by studying sections of the cortex and the
medulla. Note the frequent appearance of arcuate artery and vein profiles along the
boundary between the cortex and the medulla (B-67, H&E [2.5x-labeled, 10x, 20x, 40x-labeled]).
TheKidney